Takecab Tablets 20mg 100tab.
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Dosage form
- Tablets: oval, pale red in color, measuring 11.2 mm × 6.2 mm × 3.9 mm.
- Packaging: 100 tablets.
Please note that the appearance of the packaging may vary depending on the manufacturer and region of sale.
Active ingredient
Vonoprazane fumarate — potassium is a competitive proton pump blocker that inhibits gastric acid secretion.
Dosage
- Gastric ulcer: 20 mg once a day for up to 8 weeks.
- Duodenal ulcer: 20 mg once a day for up to 6 weeks.
- Reflux esophagitis: 20 mg once a day for up to 4 weeks; if necessary, the course can be extended to 8 weeks.
- Prevention of recurrence of ulcers associated with taking aspirin or NSAIDs: 10 mg once a day.
- Eradication of Helicobacter pylori: 20 mg twice daily in combination with clarithromycin and amoxicillin for 7 days.
Takecab is the trade name of a medication containing vonoprazan, a potassium-competitive acid blocker (P-CAB) used to treat conditions associated with increased gastric acid secretion.
Indications for Use:
- Peptic Ulcer Disease:
- Treatment of gastric and duodenal ulcers.
- Reflux Esophagitis:
- Management of erosive and non-erosive reflux disease.
- Prevention of NSAID- or Aspirin-Associated Ulcers:
- Reduces the risk of recurrent gastric or duodenal ulcers in patients taking low-dose aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs).
- Eradication of Helicobacter pylori:
- Used in combination with antibacterial agents for the eradication of H. pylori.
Contraindications:
- Known hypersensitivity to vonoprazan or any components of the drug.
- Severe Hepatic or Renal Failure: Use is contraindicated or requires extreme caution.
- Pregnancy and Breastfeeding: Not recommended due to insufficient safety data.
Side Effects:
- Gastrointestinal System:
- Constipation, diarrhea, bloating, nausea.
- Skin Reactions:
- Rash, pruritus (itching).
- Other:
- Edema, headache.
Special Instructions:
- Patients with Liver or Kidney Impairment:
- Caution is advised, and dose adjustments may be necessary based on the severity of impairment.
- Drug Interactions:
- Vonoprazan is metabolized via enzymes such as CYP3A4, CYP2B6, CYP2C19, CYP2D6, and SULT2A1. Potential drug interactions should be assessed, especially with medications that utilize the same metabolic pathways.
- Consultation Required:
- Before starting Takecab, consult a healthcare provider to determine the appropriateness of therapy and establish the optimal dosage. Self-medication is strongly discouraged and may result in adverse outcomes.
