Rifampicin Capsules 150mg 100cap.
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Dosage form
- Capsules for oral administration: 150 mg of the active substance.
- Packaging: 100 capsules.
Please note that the appearance of the packaging may vary depending on the manufacturer and region of sale.
Active ingredient
Rifampicin is an antibiotic from the ansamycin group that has a bactericidal effect by inhibiting RNA synthesis in a bacterial cell.
Dosage
For adults:
- For tuberculosis: 450-600 mg (3-4 capsules) 1 time per day on an empty stomach.
- For other infections: 600-1200 mg per day, divided into 2 doses.
For children:
- In tuberculosis: 10-20 mg / kg of body weight 1 time per day.
The duration of treatment is determined individually depending on the disease and the response to therapy.
Rifampicin is a semi-synthetic broad-spectrum antibiotic primarily used for the treatment of tuberculosis and infections caused by susceptible microorganisms.
Indications for Use:
- Tuberculosis:
- Pulmonary and extrapulmonary tuberculosis (as part of combination therapy).
- Leprosy.
- Severe Staphylococcal Infections:
- Includes osteomyelitis and pneumonia, particularly when other antibiotics are ineffective.
- Prevention of Meningococcal Meningitis:
- For individuals who have been in close contact with patients.
Contraindications:
- Known hypersensitivity to rifampicin or any components of the drug.
- Severe liver disease (e.g., jaundice).
- Pregnancy and Breastfeeding: Use only if the potential benefits outweigh the risks.
Side Effects:
- Gastrointestinal System:
- Nausea, vomiting, diarrhea.
- Elevated liver enzyme levels (e.g., ALT, AST).
- Allergic Reactions:
- Skin rash, pruritus (itching), eosinophilia.
- Nervous System:
- Headache, dizziness.
- Hematopoietic System:
- Thrombocytopenia, leukopenia.
- Other:
- Red-orange discoloration of urine, tears, saliva, and other bodily fluids (a harmless but notable effect).
Special Instructions:
- Liver Function Monitoring:
- Regular monitoring of liver enzymes is recommended, particularly in patients with pre-existing liver conditions or prolonged use.
- Drug Interactions:
- Rifampicin can reduce the efficacy of certain medications, including oral contraceptives, anticoagulants, and antiepileptics. Medical consultation is essential to manage interactions.
- Laboratory Test Interference:
- Rifampicin may affect the results of some laboratory tests, including liver function and diagnostic tests for infectious diseases.
- Consultation Required:
- Before initiating treatment with Rifampicin, consult a healthcare provider to assess the appropriateness of therapy and determine the optimal dosage. Self-medication is strongly discouraged and may lead to adverse outcomes.
