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Rifampicin Capsules 150mg 100cap.
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Manufacturer: Sanofi
Active ingredient:
Shelf life: Generally 2-3 years (24-36 months) from date of manufacture - exact shelf life is indicated on the packaging - use strictly until expiration date
Current price
$46
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Storage conditions
Store at a temperature not exceeding 25°C - Keep away from moisture and sunlight - Store in original packaging - Keep out of reach of children

Rifampicin is a semi-synthetic broad-spectrum antibiotic primarily used for the treatment of tuberculosis and infections caused by susceptible microorganisms.

Indications for Use:

  1. Tuberculosis:
    • Pulmonary and extrapulmonary tuberculosis (as part of combination therapy).
  2. Leprosy.
  3. Severe Staphylococcal Infections:
    • Includes osteomyelitis and pneumonia, particularly when other antibiotics are ineffective.
  4. Prevention of Meningococcal Meningitis:
    • For individuals who have been in close contact with patients.

Contraindications:

  • Known hypersensitivity to rifampicin or any components of the drug.
  • Severe liver disease (e.g., jaundice).
  • Pregnancy and Breastfeeding: Use only if the potential benefits outweigh the risks.

Side Effects:

  1. Gastrointestinal System:
    • Nausea, vomiting, diarrhea.
    • Elevated liver enzyme levels (e.g., ALT, AST).
  2. Allergic Reactions:
    • Skin rash, pruritus (itching), eosinophilia.
  3. Nervous System:
    • Headache, dizziness.
  4. Hematopoietic System:
    • Thrombocytopenia, leukopenia.
  5. Other:
    • Red-orange discoloration of urine, tears, saliva, and other bodily fluids (a harmless but notable effect).

Special Instructions:

  1. Liver Function Monitoring:
    • Regular monitoring of liver enzymes is recommended, particularly in patients with pre-existing liver conditions or prolonged use.
  2. Drug Interactions:
    • Rifampicin can reduce the efficacy of certain medications, including oral contraceptives, anticoagulants, and antiepileptics. Medical consultation is essential to manage interactions.
  3. Laboratory Test Interference:
    • Rifampicin may affect the results of some laboratory tests, including liver function and diagnostic tests for infectious diseases.
  4. Consultation Required:
    • Before initiating treatment with Rifampicin, consult a healthcare provider to assess the appropriateness of therapy and determine the optimal dosage. Self-medication is strongly discouraged and may lead to adverse outcomes.

Capsules for oral administration
 - dosage: 150 mg
 - may also be available in other dosages (e.g. 300 mg)
 - Other forms are also available: tablets, injectable solution, suspensions - depending on the manufacturer 

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