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Rabefine PACK 7sheet.
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Manufacturer: Eisai Co., Ltd.
Active ingredient:
Shelf life: 2–3 years (specified on the packaging), subject to storage conditions.
Current price
$54
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Storage conditions
Store at a temperature not exceeding 25°C. Keep away from moisture and direct sunlight. Store in the original packaging, out of reach of children.

Rabefine Pack is a combination therapy designed for the eradication of Helicobacter pylori in patients with stomach and duodenal diseases.

Indications for Use:

  • Eradication of Helicobacter pylori in patients with:
    • History of gastric or duodenal ulcers following endoscopic treatment.
    • Gastric MALT lymphoma.
    • Idiopathic thrombocytopenic purpura (ITP).
    • Early-stage gastric cancer.
    • Helicobacter-associated gastritis.

Contraindications:

  • Known hypersensitivity to any components of the drug.
  • Severe liver or kidney dysfunction.
  • Pregnancy and breastfeeding.

Side Effects:

  1. Gastrointestinal System:
    • Nausea, diarrhea, abdominal pain.
  2. Allergic Reactions:
    • Skin rash, pruritus (itching).
  3. Nervous System:
    • Headache, dizziness.

Special Instructions:

  1. Antibiotic Sensitivity Testing:
    • Before initiating therapy, conduct a test to determine H. pylori sensitivity to antibiotics included in the regimen.
  2. Alcohol Avoidance:
    • Avoid alcohol consumption during treatment, as it may cause a disulfiram-like reaction when combined with metronidazole.
  3. Severe Side Effects:
    • If severe adverse reactions occur, discontinue use and consult a healthcare provider promptly.
  4. Consultation Recommended:
    • Before using Rabefine Pack, consult a healthcare provider to determine the appropriateness of therapy and establish an optimal treatment regimen. Self-medication is strongly discouraged and may lead to undesirable outcomes.

A set (blister/sheet - sheet) of combination therapy including tablets and capsules.
 Each sheet contains a daily dose of three medicines that are taken twice a day (morning and evening).

Usually one sheet (sheet) includes:

  • Rabeprazole sodium 10 mg - 2 tablets
  • Amoxicillin 750 mg - 4 capsules
  • Clarithromycin 200 mg - 2 tablets.

Each set of 7 sheets is designed for a 7-day course of treatment, which is the standard regimen for H. pylori eradication in Japan and several other countries.

Translated with DeepL.com (free version)

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