
Rabefine Pack is a combination therapy designed for the eradication of Helicobacter pylori in patients with stomach and duodenal diseases.
Indications for Use:
- Eradication of Helicobacter pylori in patients with:
- History of gastric or duodenal ulcers following endoscopic treatment.
- Gastric MALT lymphoma.
- Idiopathic thrombocytopenic purpura (ITP).
- Early-stage gastric cancer.
- Helicobacter-associated gastritis.
Contraindications:
- Known hypersensitivity to any components of the drug.
- Severe liver or kidney dysfunction.
- Pregnancy and breastfeeding.
Side Effects:
- Gastrointestinal System:
- Nausea, diarrhea, abdominal pain.
- Allergic Reactions:
- Skin rash, pruritus (itching).
- Nervous System:
- Headache, dizziness.
Special Instructions:
- Antibiotic Sensitivity Testing:
- Before initiating therapy, conduct a test to determine H. pylori sensitivity to antibiotics included in the regimen.
- Alcohol Avoidance:
- Avoid alcohol consumption during treatment, as it may cause a disulfiram-like reaction when combined with metronidazole.
- Severe Side Effects:
- If severe adverse reactions occur, discontinue use and consult a healthcare provider promptly.
- Consultation Recommended:
- Before using Rabefine Pack, consult a healthcare provider to determine the appropriateness of therapy and establish an optimal treatment regimen. Self-medication is strongly discouraged and may lead to undesirable outcomes.
A set (blister/sheet - sheet) of combination therapy including tablets and capsules.
Each sheet contains a daily dose of three medicines that are taken twice a day (morning and evening).
Usually one sheet (sheet) includes:
- Rabeprazole sodium 10 mg - 2 tablets
- Amoxicillin 750 mg - 4 capsules
- Clarithromycin 200 mg - 2 tablets.
Each set of 7 sheets is designed for a 7-day course of treatment, which is the standard regimen for H. pylori eradication in Japan and several other countries.
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