Nichiphargen Inj. 20ml 50polyethilene vial
Dosage form
  • Solution for injection: 20 ml polyethylene vials.
  • Package: 50 vials.
Please note that the appearance of the packaging may vary depending on the manufacturer and region of sale.
Active ingredient

Sodium heparin is a direct—acting anticoagulant that prevents the formation of blood clots and promotes their resorption.

Dosage
  • For adults: the dosage is selected individually depending on the indications and the clinical situation.

Methods of administration:

  • Intravenous: bolus injection or infusion.
  • Subcutaneously: usually injected into the abdominal area.

Therapy monitoring: Regular monitoring of blood clotting parameters, such as activated partial thromboplastin time (APTT), is recommended.


Nichiphargen Injection contains sodium heparin, a direct-acting anticoagulant used for the prevention and treatment of thromboembolic diseases.

Indications for Use:

  1. Prevention and Treatment of Thromboembolic Diseases:
    • Deep vein thrombosis (DVT).
    • Pulmonary embolism (PE).
    • Thrombophlebitis.
  2. Prevention of Blood Clotting:
    • During hemodialysis.
    • In cardiovascular surgery and other vascular procedures.
    • In laboratory settings.

Contraindications:

  • Hypersensitivity to heparin or any components of the drug.
  • Active Bleeding or conditions with a high risk of bleeding.
  • Heparin-Induced Thrombocytopenia (HIT).
  • Severe hepatic or renal failure.
  • Uncontrolled arterial hypertension.
  • Recent surgical procedures involving the brain, spinal cord, or eyes.

Side Effects:

  1. Bleeding:
    • Of various localizations and severities.
  2. Thrombocytopenia:
    • Decrease in platelet count, including heparin-induced thrombocytopenia.
  3. Allergic Reactions:
    • Skin rash, pruritus (itching), urticaria (hives), and rare anaphylactic reactions.
  4. Osteoporosis:
    • Associated with prolonged use.
  5. Liver Function:
    • Elevated liver enzyme levels.

Special Instructions:

  1. Therapy Monitoring:
    • Regular monitoring of blood coagulation parameters (e.g., activated partial thromboplastin time [aPTT]) and platelet counts is required.
  2. Drug Interactions:
    • Use with caution when combined with other anticoagulants, antiplatelet agents, or nonsteroidal anti-inflammatory drugs (NSAIDs), as the risk of bleeding increases.
  3. Pregnancy and Lactation:
    • Use only under strict medical indications and close supervision by a healthcare provider.
  4. Consultation Required:
    • Before initiating treatment with Nichiphargen Injection, consult a physician to evaluate the appropriateness of therapy and determine the optimal dosage. Self-medication is strongly discouraged and may result in severe adverse effects.
Nichiphargen Inj. 20ml 50polyethilene vial