Melex is the trade name of a medication containing mexazolam, a benzodiazepine class drug. It is used for the treatment of anxiety disorders, whether associated with psychoneurotic conditions or not.

Indications for Use:

• Anxiety Disorders:
  • Associated or not associated with psychoneurotic conditions.

Contraindications:

• Known hypersensitivity to mexazolam or other benzodiazepines.
• Myasthenia Gravis.
• Severe respiratory depression.
• Obstructive Sleep Apnea Syndrome (nocturnal apnea).
• Severe hepatic insufficiency.
• Pregnancy and breastfeeding.

Side Effects:

1. Central Nervous System:
   • Drowsiness, dizziness, decreased concentration, fatigue, ataxia.
2. Digestive System:
   • Nausea, dry mouth, constipation.
3. Allergic Reactions:
   • Skin rash, pruritus (itching).
4. Other:
   • Muscle weakness.
   • Dependence with prolonged use.

Special Instructions:

1. Risk of Dependence:
   • Prolonged use of mexazolam may result in the development of physical and psychological dependence. Use the lowest effective dose for the shortest possible duration.
2. Drug Withdrawal:
   • Abrupt discontinuation may lead to withdrawal syndrome. Gradual dose reduction under medical supervision is strongly recommended.
3. Effect on Driving and Machinery Operation:
   • The drug may impair concentration and psychomotor reaction speed. Avoid driving vehicles or operating machinery during treatment.
4. Interaction with Alcohol:
   • Concurrent use with alcohol enhances the sedative effect and is not recommended.
5. Consultation Recommended:
   • Before initiating treatment with Melex, consult a healthcare provider to evaluate the appropriateness of therapy and determine the optimal dosage. Self-medication is discouraged and may result in adverse effects.