Mexitil Capsules 100mg 100cap.
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Dosage form
- Capsules: 100 mg of mexiletine each.
- Packaging: 100 capsules.
Please note that the appearance of the packaging may vary depending on the manufacturer and region of sale.
Active ingredient
Mexiletine is a class IB antiarrhythmic drug that stabilizes cardiomyocyte membranes and reduces their excitability.
Dosage
- Adults: the starting dose is usually 200 mg (2 capsules of 100 mg) every 8 hours.
- Maintenance dose: may be adjusted depending on clinical response and tolerability, usually between 200 mg and 300 mg every 8 hours.
- Maximum daily dose: should not exceed 1200 mg.
- How to use: capsules are taken orally, drinking enough water, regardless of meals.
Mexitil is the trade name for a medication containing mexiletine, a class IB antiarrhythmic agent. It is used for the treatment and prevention of various cardiac rhythm disorders.
Indications for Use:
- Ventricular Arrhythmias:
- Treatment and prevention of symptomatic ventricular arrhythmias, including ventricular tachycardia.
- Supraventricular Arrhythmias:
- For cases where other treatment options are ineffective or contraindicated.
Contraindications:
- Known hypersensitivity to mexiletine or any components of the drug.
- Cardiogenic Shock.
- Sick Sinus Syndrome, unless a pacemaker is present.
- Second- or Third-Degree Atrioventricular Block, unless the patient has a pacemaker.
- Severe bradycardia.
Side Effects:
- Central Nervous System:
- Dizziness, tremor, blurred vision, headache, nervousness, drowsiness.
- Gastrointestinal System:
- Nausea, vomiting, heartburn, abdominal pain.
- Cardiovascular System:
- Hypotension, worsening of arrhythmias, bradycardia.
- Allergic Reactions:
- Skin rash, pruritus (itching).
Special Instructions:
- Therapy Monitoring:
- Regular monitoring of ECG and plasma mexiletine levels is recommended to optimize dosage and minimize the risk of side effects.
- Hepatic and Renal Impairment:
- In patients with liver or kidney dysfunction, dose adjustments and careful monitoring are necessary.
- Drug Interactions:
- Mexiletine may interact with other antiarrhythmic agents, beta-blockers, and CYP2D6 inhibitors. Use caution when combining therapies.
- Pregnancy and Lactation:
- Use is permitted only under strict medical indications and supervision.
- Consultation Recommended:
- Before initiating treatment with Mexitil, consult a healthcare provider to evaluate the appropriateness of therapy and determine the optimal dosage. Self-medication is not advised and may result in adverse effects.
