MECOBALAMIN Injection 0.5mg 1ml (ISEI) (Vitamin B12) 50amp.
Dosage form
  • Solution for injection: 0.5 mg of mecobalamin in 1 ml of solution.
  • Packaging: 50 ampoules of 1 ml.
Please note that the appearance of the packaging may vary depending on the manufacturer and region of sale.
Active ingredient

Mecobalamin is a coenzyme form of vitamin B₁₂, involved in the synthesis of methionine and nucleic acids, as well as in the metabolism of folate.

Dosage
  • Adults: usually administered 0.5 mg (1 ampoule) intramuscularly or intravenously once daily.
  • Course of treatment: depends on the severity of the disease and the patient's response to therapy; may be from several weeks to several months.
  • Children: dosage is determined individually, depending on age, body weight and clinical situation.

Mecobalamin is the active coenzyme form of vitamin B₁₂, used in the treatment of various neurological and hematological disorders.

Indications for Use:

  1. Pernicious Anemia.
  2. Megaloblastic Anemia caused by vitamin B₁₂ deficiency.
  3. Diabetic and Alcoholic Polyneuropathy.
  4. Trigeminal Neuralgia.
  5. Down Syndrome.
  6. Infantile Cerebral Palsy.
  7. Peripheral Nerve Injuries.

Contraindications:

  • Known hypersensitivity to mecobalamin or any other components of the drug.
  • Erythremia, erythrocytosis, or thromboembolism.

Side Effects:

  1. Allergic Reactions:
    • Skin rash, pruritus (itching), urticaria (hives).
  2. Cardiovascular System:
    • Tachycardia, chest pain (pain in the heart area).
  3. Nervous System:
    • Headache, dizziness, agitation.
  4. Other:
    • Diarrhea, hypercoagulability when used in high doses.

Special Instructions:

  1. Monitoring Blood Parameters:
    • Regular monitoring of peripheral blood parameters is recommended during prolonged use.
  2. Drug Interactions:
    • Mecobalamin may enhance allergic reactions caused by thiamine.
    • Avoid combining with drugs that increase blood coagulation.
  3. Pregnancy and Lactation:
    • Use is permitted only under strict medical indications and supervision.
  4. Consultation Recommended:
    • Before starting treatment with Mecobalamin, consult a healthcare provider to assess the appropriateness of therapy and determine the optimal dosage. Self-medication is strongly discouraged and may result in adverse effects.
MECOBALAMIN Injection 0.5mg 1ml (ISEI) (Vitamin B12) 50amp.