Crestor is a hypolipidemic drug used to reduce cholesterol levels and prevent cardiovascular disease.

Active substance:

• Rosuvastatin (in the form of rosuvastatin calcium)

Form of release:

• Film-coated tablets in the following dosages:
  • 5 mg
  • 10 mg
  • 20 mg
  • 40 mg

Tablet description:

• 5 mg: round, biconvex, yellow in color, engraved “ZD4522 5” on one side.
• 10 mg: round, biconvex, pink in color, engraved “ZD4522 10” on one side.
• 20 mg: round, biconvex, pink, with engraving “ZD4522 20” on one side.
• 40 mg: oval, biconvex, pink in color, with engraving “ZD4522” on one side and “40” on the other.

Indications for use:

• Primary hypercholesterolemia (type IIa according to Fredrickson), including familial heterozygous hypercholesterolemia.
• Mixed hypercholesterolemia (type IIb).
• Familial homozygous hypercholesterolemia.
• Hypertriglyceridemia (Fredrickson type IV).
• Slowing the progression of atherosclerosis.
• Prevention of cardiovascular complications in patients at increased risk of their development.

Dosage and method of administration:

• Initial dose: 5 or 10 mg once daily, regardless of meals.
• Dose adjustment: if necessary, the dose can be increased after 4 weeks.
• Maximum dose: 40 mg per day, prescribed in exceptional cases in patients with severe hypercholesterolemia and high risk of cardiovascular complications.

Contraindications:

• Hypersensitivity to rosuvastatin or other components of the drug.
• Liver disease in the active phase.
• Severe renal insufficiency.
• Myopathy.
• Concomitant administration of cyclosporine.
• Pregnancy and period of breastfeeding.

Before use, it is recommended to consult a physician to determine the optimal dosage and assess possible risks.