Adults: from 100 to 500 mg (2-10 ml of 5% solution) per day, in scurvy therapy - up to 1000 mg per day.
Children: from 100 to 300 mg (2-6 ml of 5% solution) per day, in scurvy therapy - up to 500 mg (10 ml of 5% solution) per day.
The drug is administered intravenously (slowly) or intramuscularly. Duration of treatment depends on the nature and course of the disease.
Ascorbic acid (vitamin C) is a water-soluble vitamin necessary for the normal functioning of the body. It is involved in the synthesis of collagen, amino acid metabolism, iron absorption and has antioxidant properties.
Form of release: Ascorbic acid for injection is available as a solution for intravenous and intramuscular administration. The concentration of the solution can be 5% (50 mg/mL) or 10% (100 mg/mL)
Indications for use:
Prevention and treatment of hypo- and avitaminosis of vitamin C (scurvy).
Hemorrhagic diathesis, capillarotoxicosis, bleeding (nasal, after tooth extraction, pulmonary, uterine, caused by radiation sickness) as part of a complex therapy.
Increased need of the body during growth, pregnancy, lactation, with physical and mental stress.
Recovery period after infectious diseases and intoxication.
Liver disease (chronic hepatitis and cirrhosis) as part of complex therapy.
Chronic adrenal insufficiency (Addison's disease), adrenal crisis in Addison's disease.
Hypoacid gastritis, peptic ulcer disease of the stomach and duodenum, the state after gastric resection, enteritis, colitis.
Sluggish-healing wounds and ulcers, bone fractures.
Side effects:
Headache, feeling of fatigue.
Increase in blood pressure, myocardiodystrophy.
Depression of endocrine function of the pancreas (hyperglycemia, glucosuria).
Thrombocytosis, anemia, neutrophilosis, hypokalemia.
Hyperprothrombinemia, thrombosis, decreased capillary permeability and impaired tissue trophism.
Allergic reactions (including anaphylactic shock).
Renal dysfunction (glomerulopathy), urolithiasis, formation of oxalate stones.
With prolonged use of large doses: sodium and fluid retention, development of microangiopathies, metabolic disorders of zinc, copper, leading to neurotoxic effects (increased excitability of the CNS, sleep disturbance).
Contraindications:
Hypersensitivity to the components of the drug.
Hypercoagulability.
Tendency to thrombosis, thrombophlebitis.
Diabetes mellitus, hyperoxalaturia, nephrolithiasis.
Hemochromatosis, thalassemia.
Glucose-6-phosphate dehydrogenase deficiency.
Special Instructions:
In pregnancy and during breastfeeding, use only if the anticipated benefit to the mother exceeds the potential risk to the fetus or child.
The minimum daily requirement for ascorbic acid in the II-III trimesters of pregnancy is about 60 mg.
It should be borne in mind that the fetus may adapt to the high doses of ascorbic acid taken by the pregnant woman, and then the newborn may develop a “withdrawal” syndrome.
The minimum daily requirement during breastfeeding is 80 mg.
The mother's diet containing an adequate amount of ascorbic acid is sufficient to prevent its deficiency in the infant.
Theoretically, there is a risk to the child when the mother uses high doses of ascorbic acid (it is recommended not to exceed the daily requirement of ascorbic acid by a nursing mother).
It is recommended to consult a physician before starting to use the drug.
